The game will force you to experiment with squad compositions due to various afflictions preventing you from running the same squad endlessly, but this acts as a strength, since finding a good squad composition can be a rather pleasing experience. Although the game lacks much depth in regards to armor or weapons (all Crusaders will use the same weapons and armor, all Lepers use the same weapons and armor, etc), characters can differentiate themselves thanks to their own personal quirks, their exact skillset and their trinkets carried, all of which is further amplified by the concrete class composition of each individual squad. The game seeks to make each victory a satisfying experience, and on that front it largely succeeds.
A nice challenge with plenty of depth For players that lean more towards a challenging, satisfying experience akin to something like Dark Souls, Darkest Dungeon doesn't compromise on difficulty.